Spammers are getting especially annoying these days, with targeted messages.
I have been striking back, though. My honey pot has recently caught a few of them red-handed, to be reported to such authorities as there are for such things.
If you run a web server and you want to help combat the scourge of spam, consider joining Project Honeypot.
You get a certain definite measure of satisfaction when they email you to let you know that your honeypot has helped to identify a server contributing to spam, such as by harvesting email addresses.
So far, I have contributed to the identification of a few dozen malicious IP addresses, hopefully preventing quite a lot of spam.